Psammoma body
A psammoma body is a round collection of calcium, seen microscopically. The term is derived from the Greek word psammos meaning "sand."
Etiology
Psammoma bodies are associated with the papillary (nipple-like) histomorphology and are thought to arise from (1) the infarction and calcification of papillae tips and (2) calcification of intralymphatic tumor thrombi.[1]
Association with malignant lesions
Psammoma bodies are commonly seen in certain tumors such
Benign lesions
Psammoma bodies may be seen in:
Appearance
Psammoma bodies usually have a laminar appearance, are circular, acellular and eosinophilic.
References
- ^ Johannessen JV, Sobrinho-Simões M (September 1980). "The origin and significance of thyroid psammoma bodies". Lab. Invest. 43 (3): 287–96. PMID 7401638.
- ^ Ovarian papillary serous cystadenocarcinoma at WebPath, The Internet Pathology Laboratory for Medical Education at Mercer University School of Medicine. Retrieved July 2011
- ^ 10.1148/rg.306105523 October 2010 RadioGraphics, 30, 1445-1464
- ^ Robbin's Pathology, Eight Ed
- ^ Hallman KB, Nahhas WA, Connelly PJ (September 1991). "Endosalpingiosis as a source of psammoma bodies in a Papanicolaou smear. A case report". J Reprod Med 36 (9): 675–8. PMID 1774734.
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